THE PORTAL TRANSPORT OF ABSORBED FATTY ACIDS
نویسندگان
چکیده
منابع مشابه
The portal transport of absorbed fatty acids.
Earlier reports have shown that absorbed U4-labeled stearic (l), palmitic (2), and pentadecanoic (3) acids can be recovered, almost quantitatively, in intestinal or thoracic duct lymph. In the case of myristic acid, however, the highest recovery in lymph was about 80, and the lowest about 60 per cent of the absorbed C14. Still lower values (15 to 55 per cent) were observed with lauric acid, and...
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Recently, we investigated the path by which an absorbed, long chain fatty acid leaves the intestine (1). Unanesthetized rats, into whose thoraric ducts or lacteals cannulae had been introduced, were fed C4-labeled palmitic acid as either the triglyceride or the free acid. From 70 to 92 per cent of the absorbed, labeled fatty acid was recovered as fatty acid Cl4 from the thoracic duct lymph in n...
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Long-chain fatty acids (LCFAs) are vital components of our diet and contribute to a plethora of processes including metabolic energy generation and storage, plasma membrane synthesis, and protein anchoring. In addition, LCFAs have hormone-like properties since they can profoundly affect gene expression via nuclear receptors such as HNF4 and the PPAR family (reviewed in Ref. 45), trigger insulin...
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ECENT studies with C14-labeled palmitic and pentadecanoic acids have shown R that, after their absorption, these fatty acids can be recovered almost quantitatively from intestinal or thoracic duct lymph (I, 2). Since there are indications in the literature that a short-chain fatty acid, such as butyric, does not, to any appreciable extent, make use of lymph (3), we have inquired into the specif...
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The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. Genetic and biochemical studies in the yeast Saccharomyces cerevisiae have identified enzymes for r...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1952
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)44850-8